[PDF][PDF] Clonal analysis of mouse development reveals a polyclonal origin for yolk sac blood islands

H Ueno, IL Weissman - Developmental cell, 2006 - cell.com
… , we established multichimera mice wherein three different ES … that each yolk sac blood
island is derived from multiple clonal … to the same island, and that most blood cells do not derive …

[PDF][PDF] The origin and fate of yolk sac hematopoiesis: application of chimera analyses to developmental studies

H Ueno, IL Weissman - International Journal of Developmental Biology, 2010 - ijdb.ehu.es
… , hematopoietic cells first appear in the yolk sac blood islands… of one particular tissue of
interest is monoclonal or polyclonal… positive and negative cells, it shows that more than one type …

Clonal analysis identifies hemogenic endothelium as the source of the blood-endothelial common lineage in the mouse embryo

L Padrón-Barthe, S Temiño… - Blood, The Journal …, 2014 - ashpublications.org
… in close association in the blood islands of the yolk sac (YS). … embryos shows that a fraction
of the endothelium- and blood-… Therefore, the frequency of polyclonal monocolor clusters can …

Both primitive and definitive blood cells are derived from Flk-1+ mesoderm

JJ Lugus, C Park, YD Ma, K Choi - Blood, The Journal of the …, 2009 - ashpublications.org
mice with Flk1 −/− embryonic stem (ES) cells, it was revealed … the yolk sac blood islands
of E8.5 Flk1 +/Cre ;Rosa26R-LacZ … way to look for populations of clonal cells would be via 3-…

[PDF][PDF] In vivo clonal analysis reveals lineage-restricted progenitor characteristics in mammalian kidney development, maintenance, and regeneration

Y Rinkevich, DT Montoro, H Contreras-Trujillo… - Cell reports, 2014 - cell.com
Analysis of mice derived by transfer of color-marked embryonic stem cells (ESCs) into
uncolored blastocysts demonstrates that nephrons are polyclonal, developing from expansions of …

Definitive hematopoiesis in the yolk sac emerges from Wnt-responsive hemogenic endothelium independently of circulation and arterial identity

JM Frame, KH Fegan, SJ Conway, KE McGrath… - Stem …, 2016 - academic.oup.com
blood flow and oxygenation of the growing murine embryo [16, … This analysis revealed a
population of CD41 hi Kit neg cells … of the blood island region of the proximal yolk sac (above the …

The sialomucin CD34 is expressed on hematopoietic cells and blood vessels during murine development

PE Young, S Baumhueter, LA Lasky - 1995 - ashpublications.org
… hematopoietic system as blood islands in the yolk sac is followed … Analysis of vessels in
developing brain shows that these … 1, this polyclonal antibody also specifically recognizes blood

Clonal analysis of human embryonic stem cell differentiation into teratomas

B Blum, N Benvenisty - Stem Cells, 2007 - academic.oup.com
… , we show that this tumor is polyclonal, derived from all cells … All mice developed teratomas,
which were extracted 4 weeks … coupled to DNA microsatellite analysis shows that there is …

Etv2 Is Expressed in the Yolk Sac Hematopoietic and Endothelial Progenitors and Regulates Lmo2 Gene Expression

N Koyano‐Nakagawa, J Kweon, M Iacovino, X Shi… - Stem Cells, 2012 - academic.oup.com
… this study, we define the role of Etv2 in yolk sac blood island … the hematopoietic lineages in
a blood island are not clonal [9]. These … Our immunohistological analysis shows that EYFP is …

Erythropoiesis: development and differentiation

E Dzierzak, S Philipsen - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Yolk sac blood islands containing primitive erythrocytes are … before vascularization revealed
that the adult blood system of … Clonal analysis has shown that F cells are derived from the …